A glebe house was the official residence of a Church of Ireland rector, provided from glebe land, that is, land set aside by the parish for the maintenance of its Protestant clergyman. These houses were built in considerable numbers across Ireland from the late eighteenth century onwards, often with financial assistance from the Board of First Fruits, a body that disbursed funds for ecclesiastical construction. They tend to be plain, solidly built affairs, Georgian or early Victorian in character, and their presence in a townland is almost always a marker of the Established Church's former reach into a predominantly Catholic countryside.

The glebe house at Moylough More sits within that broader pattern, though the specific details of its construction, its rectors, and its subsequent history remain to be fully documented. What can be said is that Moylough itself has a long ecclesiastical character; the area gives its name to one of the most remarkable early medieval objects ever found in Ireland, the Moylough Belt Shrine, an eighth-century reliquary of silver and gilt bronze discovered in a nearby bog in 1945 and now held in the National Museum. The presence of a later Protestant glebe house in the same landscape is a reminder of how thoroughly the religious geography of a single place can shift across the centuries, from early Christian devotion, through medieval parish structures, to the planted Established Church of the post-Reformation period.